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Description
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Biochem/physiol Actions A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Properties
color white with slight yellow cast
mp 215 °C (dec.)(lit.)
solubility H2O: 50 mg/mL
storage temp. 2-8°C
Safety
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes Xi
Risk Statements 42/43
Safety Statements 22-36/37-45
WGK Germany 2
RTECS XH8400000
References
reference Raleigh, E.A., Ausubel, M., et al. Short Protocols in Molecular Biology 2nd ed., New York, NY , (1992) 12, 2
Perlman, D., et al., Use of antibotics in cell culture. Meth. Enzymol. LVIII, 112, (1979)
Merck Merck 13,591
Corp MSDS 1 (1), 247:C / RegBook 1 (2), 2065:J / Sax 6, 2410 / Sigma FT-IR 1 (1), 619:B / Structure Index 1, 328:C:3
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