Anti- CD64/IGFR1/FCGR1A/FITC抗体说明书
From:ABCAM
Catalog Number :RS- 3511R-FITC
Quantity size : 0.1ml (dilute with pH 7.4 0.01 M PBS or antibody diluent ) Background: The high affinity receptor for immunoglobulin G CD64 is encoded by a family of 3 genes that share over 98% of DNA sequence homology: FCGR1A, FCGR1B and FCGR1C. The FCGR1C gene, like FCGR1A, is located on 1q21. The third gene of this family, FCGR1B, was found at 1p12. CD64 plays a pivotal role in the immune response. It is a glycoprotein (MW 72 kD) that is constitutively expressed on human monocytes and macrophages.
Subunit : Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL. Interacts with HCK and LYN.
Subcellular Location : Cell membrane; Single-pass type I membrane protein. Note=Stabilized at the cell membrane through interaction with FCER1G.
Tissue Specificity : Monocyte/macrophage specific.
Similarity : Belongs to the immunoglobulin superfamily. FCGR1 family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Specificity : Anti- CD64/IGFR1/FCGR1A/FITCis a rabbit polyclonal antibody
specific for CD64/IGFR1/FCGR1A/FITC of Human, Mouse, Rat, Pig, Cow,
use for western blotting,elisa,immunoprecipitation and immunohistochemistry
Application :
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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