产品编号 yb-8247R
英文名称 Anti-COBL抗体
中文名称 耳聋-甲状腺肿综合征相关COBL蛋白抗体
别 名 cobL; COBL_HUMAN; DKFZp686G13227; KIAA0633; MGC131893; Protein cordon-bleu.
Anti-COBL抗体
说 明 书 0.1ml 0.2ml
研究领域 心血管 细胞生物 免疫学 发育生物学 神经生物学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 136kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human COBL
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Cordon-bleu, also known as COBL, is a 1,261 amino acid protein that localizes to the node of the axial midline, a structure that organizes morphogenesis of the vertebrate embryo. Widely conserved and existing as five alternatively spliced isoforms, Cordon-bleu interacts with Vangl2 to mediate closure of the midbrain neural tube and is highly expressed in pancreas, ovary, brain, liver, lung and kidney. Cordon-bleu contains three WH2 domains and is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.
Similarity:
Contains 3 WH2 domains.
Database links:
UniProtKB/Swiss-Prot: O75128.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
上海钰博生物科技有限公司是2012年5月由“海归”组成的创业团队与两个专业投资机构发起成立的，以开发生产科研试剂和特色检验产品为方向，经过两年多的努力，已经建立了免疫学和分子生物学的五个技术平台，开发了ELISA/ELISpot酶联免疫试剂盒、重组蛋白、荧光标记抗体、四聚体（Tetramer）特异性T细胞检测试剂盒、Aimplex流式高通量多因子检测、microRNA 表达谱分析和功能研究等系列产品和服务，研究论文在Nature、Eur. J. Immunol、The Journal of Immunology和Arthritis & Rheumatism等学术期刊上发表，与国内外免疫学、干细胞、传染病和肿瘤研究及临床检验领域的科学家们建立了良好的合作关系，形成了一定的品牌影响力。
钰博生物另建有七大技术服务平台（ELISA定制服务，免疫学检测服务、分子生物学技术服务、蛋白表达与纯化技术服务、抗体制备技术服务、细胞培养技术服务、整体实验课题服务）并代理国外试剂：abcam 抗体；MBL，eBioscience，BD，R&D,Santan,CST,RayBiotech等品牌试剂，用专业的知识、专业的设备、专业的态度为客户提供一站式实验技术服务！
我们的优势：完善、稳定的实验体系，优秀的科研队伍，实验设备、准确可靠的实验结果。禀存用户*的原则，竭诚为您服务。质量是所有产品和服务关键的组成部分，我们通过质量和实力赢得客户的信赖。产品的质量是企业的生命。
Elisa试剂盒，检测试剂盒，抗体，生化试剂，微生物培养基，重组蛋白，血清，实验耗材等产品
Anti-COBL抗体 产品信息
