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编 号：hy030006
名 称：Anti-Nestin，巢蛋白，神经上皮干细胞蛋白抗体
来 源：兔
交叉反应：人
克隆类型：多克隆抗体
浓 度：1mg/1ml
性 状：Lyophilized or Liquid
蛋白分子量：predicted molecular weight: 178kDa
应 用：WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Anti-Nestin，巢蛋白，神经上皮干细胞蛋白抗体保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
备 注：本产品仅供科研实验使用。（This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications）
Function : Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments （IF） during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells （By similarity）.
Subunit : Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, tis protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25%. Interacts with FHOD3 （By similarity）.
Tissue Specificity : CNS stem cells.
Similarity : Belongs to the intermediate filament family.
