Description
Biochem/physiol Actions An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane1
Properties
biological source from Streptomyces chattanoogensis
assay ≥95% （HPLC）
storage temp. 2-8°C
Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
WGK Germany 3
RTECS TK3325000
References
Cited Reference 1. te Welscher, Y.M., et al., Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane. J. Biol. Chem. 283, 6393, （2008）
reference Pederson, J.C. Appl. Environ. Microbiol. 58, 1064, （1992）
Stock, R. Pharmacy Int. 2, 232, （1981）
Merck Merck 14,6427
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