名称：现货供应|Recombinant Murine IL-4

货号：214-14
规格：20ug
产地：PeproTech
Biological Activity: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues. 
Cross Reactivity: Rat, Pig Intestinal Worm. Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, Synonyms: BCGF,BCDF,B cell stimulating factor （BSF-1）.