Compound 401 *10 mg(Tocris)
免费代测ELISA试剂盒一周内出结果
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主营产品: ELISA试剂盒,生物试剂,免疫组学,生物抗体,蛋白组学,分子生物等。
Technical Data
Storage:Store at RT
Purity:>99 %
Formula:C16H15N3O2
M.Wt:281.31
Solubility:Soluble to 10 mM in DMSO and to 5 mM in ethanol
Biological Activity
Displays little affinity for other commonly studied kinases including PI 3-K, ATM and ATR (IC50 values are all > 100 μM). Induces apoptosis in vitro. Chemical Name: 2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one. Reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) (IC50 values are 0.28 and 5.3 μM respectively).
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