p44/42 MAPK （Erk1/2） Control Proteins100 ul（CST）
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42. Mitogen-activated protein kinases （MAPKs） are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death.
Description
MAP kinase is phosphorylated by MEK and purified free of nonphosphorylated MAP kinase. Molecular weight of MAP kinase （Erk2） protein is 42 kDa. Supplied in SDS Sample Buffer.
p44/42 are negatively regulated by a family of dual-specificity （Thr/Tyr） MAPK phosphatases, known as DUSPs or MKPs （10）, along with MEK inhibitors such as U0126 and PD98059. Supplied in SDS Sample buffer.Phosphorylated MAP Kinase Control Protein: Fully phosphorylated Erk2 protein serves as a positive control for western blotting experiments.
Directions for Use
Molecular weight of MAP kinase （Erk2） protein is 42 kDa. As controls, we recommend using 10 µl of phosphorylated and nonphosphorylated p44/42 MAP kinase control proteins. Nonphosphorylated p44/42 MAPK （Erk1/2） Control Protein: Bacterially expressed, kinase inactive, Erk2 protein serves as a negative control for Western blotting experiments. 了解更多详细信息
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