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Anti-ELAVL4/HuD抗体,ELAVL4蛋白抗体-技术指导

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产品简介

博研生物强烈*“Anti-ELAVL4/HuD抗体,ELAVL4蛋白抗体-技术指导"，品质保障，*，提供，实验无结果可免费退换！：

详细介绍

Anti-ELAVL4/HuD抗体,ELAVL4蛋白抗体-技术指导产品介绍：The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediay after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts. ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation. When Elav-like proteins associate with these ARE sites this degradation is inhibited, leading to an increased stability of the corresponding transcript. Elav proteins function within the nucleus, and they are shuttled between the nucleus and cytoplasm by a nuclear export signal, which is a regulatory feature of the Elav-like proteins as it limits their accessibility to ARE sites.

保存条件: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃

重要提示: 本产品提供仅供研究使用，不用于人类治疗或诊断.

产品名称：Anti-ELAVL4/HuD抗体,ELAVL4蛋白抗体-技术指导

产品编号：BYK-11319R

产品规格：0.1ml/0.2ml

产品价格：请

性状：Lyophilized or Liquid

浓度：1mg/1ml

亚型：IgG

贮存：贮存于-20℃.

抗体来源：本公司抗体有兔来源和鼠来源等

克隆类型：兔来源为多抗，鼠来源为单抗

产品类型：一抗

此抗体本公司有单抗和多抗，可用于免疫组化（IHC），免疫印迹（WB），酶联免疫(ELISA)，IF、IP、流式细胞术等实验（可来电索取说明）

此产品本公司有标记的一抗出售，相关标记有：Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记

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