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PLGF 1 Human/重组人胎盘生长因子-1

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PLGF 1 Human/重组人胎盘生长因子-1 产品编号：CYT-419
产品规格：2μg/10μg/1mg

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PLGF 1 Human/重组人胎盘生长因子-1

产品编号：CYT-419
产品规格：2μg/10μg/1mg

Synonyms	PIGF, PGF, PLGF-1, PlGF-2.
Introduction	PLGF is a growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration. It binds to receptor vegfr-1/flt1.
Description	Placenta Growth Factor-1 Human Recombinant produced in insect cells is a homodimer, glycosylated polypeptide chain containing 2 x 131 amino acids and having a total molecular mass of approximay 34 kDa. The PLGF-1 is purified by proprietary chromatographic techniques.
Source	Insect Cells.
Physical Appearance	Sterile Filtered White lyophilized （freeze-dried） powder.
Formulation	Each mg of contains 50mg BSA.
Solubility	It is recommended to reconstitute the lyophilized Placenta Growth Factor 1 in sterile 20mM acetic acid not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Stability	Lyophilized Placenta Growth Factor 1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PLGF1 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Purity	Greater than 90.0% as determined by（a） Analysis by RP-HPLC. （b） Analysis by SDS-PAGE.
Amino acid sequence	The sequence of the first five N-terminal amino acids was determined and was found to be Met-Leu-Pro-Ala-Val.
Biological Activity	The ED50 as determined by its ability to bind to immobilized rh-sFlt-1 in a functional ELISA. PlGF-1 human Recombinant can bind to immobilized rh-sFlt-1 （100 ng/well） with a linear range at 0.5 - 10 ng/mL.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.