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Myostatin Human, His/重组人肌肉*, His 产品编号：CYT-445

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Myostatin Human, His/重组人肌肉*, His 产品编号：CYT-445
产品规格：2μg/10μg/1mg

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Myostatin Human, His/重组人肌肉*, His

产品编号：CYT-445
产品规格：2μg/10μg/1mg

Synonyms	GDF-8, MSTN, Growth/Differentiation Factor 8,MSTN Muscle Hypertrophy.
Introduction	Myostatin （GDF-8） is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor ? superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology.
Description	Total 152AA. M.W. 16.7kDa （calculated）. N-terminal His-tag and spacer （43AA – highlighted）. The AA sequence of the human myostatin part of the fusion protein is corresponding to the UniProtKB/Swiss-Prot entry O14793. MRGSHHHHHH GMASMTGG MGRDLYDDDD KDPSSRSAVR SRRDFGLDCD EHSTESRCCR YPLTVDFEAFGWDWIIAPKR YKANYCSGEC EFVFLQKYPH THLVHQANPR GSAGPCCTPT KMSPINMLYF NGKEQIIYGKIPAMVVDRCG CS.
Source	Escherichia Coli.
Formulation	Sterile filtered （0.4μm） and lyophilized from 0.5 mg/ml in 0.05M acetate buffer, pH 4.5.
Solubility	Add 0.1M Acetate buffer pH-4 to prepare a working stock solution of approximay 0.5 mg/mL and let the lyophilized pellet dissolve compley. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10μg/ml. In higher concentrations the solubility of this antigen is limited.
Purity	Greater than 95% as determined by SDS-PAGE.
Stability	Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. The lyophilized GDF-8 remains stable until the expiry date when stored at -20°C.
Applications	Western blotting, ELISA.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.