当前位置：厦门慧嘉生物科技有限公司>>细胞因子>>Prospec >>IL 15 Human/*15

IL 15 Human/*15

返回列表页

参考价

面议

具体成交价以合同协议为准

产品型号

品牌

厂商性质代理商

所在地厦门市

在线询价收藏产品查看联系电话

联系方式：陈先生查看联系方式

更新时间：2016-05-23 01:43:18浏览次数：359次

联系我时，请告知来自环保在线

产品分类 品牌分类

  细胞因子

Prospec

全部产品列表

暂无信息

厦门慧嘉生物科技有限公司

经营模式：代理商

商铺产品：9325条

所在地区：福建厦门市

联系人：陈先生

询价 给他留言

产品简介

IL 15 Human/*15 产品编号：CYT-230
产品规格：2μg/10μg/1mg

详细介绍

慧嘉生物您实验身边的好伙伴
为客户提供“zui高品质的产品”和“的服务”
AssayBiotech CUSABIO   Immunoway Santa   Abcam   Cst   jackson   Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec
LifeSpan BD 欢迎广大客户咨询，另有大量宣传海报和小礼品赠送。
：www.biohj.com
：382603320   1284882975

：

IL 15 Human/*15

产品编号：CYT-230
产品规格：2μg/10μg/1mg

Synonyms	IL-15, MGC9721.
Introduction	The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x（L）, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
Description	Interleukin-15 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids and having a molecular mass of 12774 Dalton. The IL-15 is purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered White lyophilized （freeze-dried） powder.
Formulation	The protein was lyophilized from a concentrated （1mg/ml） solution with 5mM Tris pH 8.0.
Solubility	It is recommended to reconstitute the lyophilized Interleukin-15 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Stability	Lyophilized Interleukin-15 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL15 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
Purity	Greater than 98.0% as determined by（a） Analysis by RP-HPLC. （b） Analysis SDS-PAGE.
Amino acid sequence	The sequence of the first five N-terminal amino acids was determined and was found to be Asn-Trp-Val-Asn-Val.
Biological Activity	The ED50 as determined by the dose-dependant stimulation of the proliferation of mouse CTLL-2 was found to be < 0.5 ng/ml, corresponding to a Specific Activity of 2 x 106 IU/mg.
Protein content	Protein quantitation was carried out by two independent methods 1. UV spectroscopy at 280 nm using the absorbency value of 0.55 as the extinction coefficient for a 0.1% （1mg/ml） solution. This value is calculated by the PC GENE computer analysis program of protein sequences （InliGenetics）. 2. Analysis by RP-HPLC, using a calibrated solution of IL-15 as a Reference Standard.
Usage	Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.