Anti-Integrin alpha 4/CD49d抗体说明书,低价供应
From:ABCAM
Catalog Number :RS-0641R
Quantity size :   0.1ml  （dilute with pH 7.4    0.01 M PBS or antibody diluent ）
Background:
Integrin alpha 4 （also called CD49d） is a 150 kDa protein that possesses a large extracellular domain involved in ligand binding, a single transmembrane domain, and an intracellular regulatory domain possessing multiple sites for phosphorylation. Integrin alpha 4 forms heterodimers with integrins beta 1 and beta 7. Integrin alpha 4 is expressed on leukocytes and leukocyte precursors, neural crest cells, and developing skeletal muscles and is essential for embryogenesis, hematopoiesis, and immune responses. The presence of integrin alpha 4 promotes cell migration and inhibits cell spreading and contractility. Integrin alpha 4 function has been implicated in the pathogenesis of multiple diseases including asthma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, hepatitis C, and multiple sclerosis, and therefore, modulation of integrin alpha 4 function has become an important target for drug discovery
.Specificity : Anti-Integrin alpha 4 is a mouse   polyclonal antibody              
specific for Integrin alpha 4 of hu, mo, rat, Rb, hrs, cow   
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– Protein G affinity chromatography purification, purity :>95%
–            Anti-Integrin alpha 4/CD49d抗体说明书,低价供应 Isotype:  IgG
– mol wt:  114kDa
Application :  
–  WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 lmmunohistochem1：100-500
– not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user..
Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at lea            Anti-Integrin alpha 4/CD49d抗体说明书,低价供应st six weeks at 2-4 ℃

Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.
            Anti-Integrin alpha 4/,低价供应