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Epibatidine, ([125I]-IPH), [125I]-, 10µCi

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珀金埃尔默医学诊断产品（上海）有限公司

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产品简介

Epibatidine, labeled with 125I. Epibatidine has analgesic activities, has been shown to function as an agonist at nicotinic acetylcholine receptors, and has been shown to bind muscarinic and serotonin......

详细介绍

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligａnd binding assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New Englａnd Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX358:

Garza, A., Huang, L.Z., Son, J.H., Winzer-Serhan, U.H. (2009), Expression of nicotinic acetylcholine receptors and subunit messenger RNAs in the enteric nervous system of the neonatal rat. Neuroscience, 158 (4): 1521-1529.
Huang, L.Z., Winzer-Serhan, U.H. (2006), Effects of paraformaldehyde fixation on nicotinic acetylcholine receptor binding in adult and developing rat brain sections. J Neurosci Methods, 153 (2): 312-317.

规格

浓度	87.9 µCi/mL
检测方法	Radiometric
新鲜的很多天	First Monday of even Months
标签位置	Nominally Labeled
分子量	298.0
产品品牌名称	NEN Radiolabeled Ligands
放射性同位素	I-125
放射性核素	¹²⁵I
受体类型	Nicotinic
运输条件	干冰
特殊订购信息	This is a radioactive product - shipping address must have a license to receive radioactive materials.
治疗领域	CNS & Neurologic, Pain, Inflammation
产品尺寸	10 µCi