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珀金埃尔默医学诊断产品（上海）有限公司
珀金埃尔默医学诊断产品（上海）有限公司
Cell membranes prepared from cells stably-transfected with human Muscarinic M3 receptor, in CHO-K1 cells.
Membrane Target Systems are quality assured frozen membranes from cells that express recombinant or endogenous receptors.
We submit every batch of receptor to stringent quality control
testing that includes saturation radioligａnd binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPγS data is also provided for some of our Gi-coupled receptors.
Membranes are carefully prepared and ready for a variety of HTS applications, including radioligａnd binding (using either proximitymethods, such as FlashPlate, or classical filtration methods).
Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet.
Some of our receptors may be restricted for sale in specified countries. Please inquire.
| 检测目标类 | GPCR |
|---|---|
| 检测目标类型 | Membrane preparation |
| 检测验证 | Binding |
| G-Alpha天然受体 | Gq/G11 |
| 宿主细胞 | CHO-K1 |
| 产品品牌名称 | Membrane Target Systems |
| 受体类型 | Acetylcholine (Muscarinic), Muscarinic |
| 运输条件 | 干冰 |
| 治疗领域 | Central Nervous System, Cardiovascular, Gastrointestinal |
| 产品尺寸 | 400 units |
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