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Orexin OX1 receptor (human recombinant) AequoZen Frozen Cells

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更新时间:2022-10-15 15:12:13浏览次数:99次

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产品简介

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazin......

详细介绍

AequoZen® Double Transfected Cell Lines: orexin OX1 receptor, human recombinant, in CHO-K1 host cell. Non-propagatable cells are shipped. A detailed technical dossier includes sequence, culture conditions and pharmacological properties of the recombinant receptor. All cell lines are tested for the absence of mycoplasma. Terms and conditions apply. Some products are not available in some countries. Please inquire at your local sales office for more information.

Features:

  • Ready-to-use cells; no cell culture required (dispense and assay)
  • Fully automatable and miniaturizable to 1536
  • Enables reduction in reagents and consumable costs
  • High signal to background ratio enabling detection of agonists, antagonists and allosteric modulators
  • Robust assay (Z', CV values, solvent resistance)
  • Reduces the number of false positives from autofluorescent compounds in screening libraries
  • Option to work with cells in suspension to increase throughput
  • Amenable for use with calcium coupled ion channels and tyrosine kinase receptors

AequoZen technology is a generic GPCR technology which can be used with Gs, Gi and Gq coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal.

规格

检测目标类 GPCR
检测验证 Calcium Luminescence
自动化兼容 Yes
宿主细胞 CHO-K1
产品品牌名称 AequoZen
受体类型 Orexin
运输条件 干冰
产品尺寸 10 million cells/vial

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