Rabbit Anti- Cav-1抗体说明书，新学期*
FROM:ABCAM
Catalog Number : Ab86711
Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Background:
Beclin 1 is the first identified mammalian gene to mediate autophagy and also has tumor suppressor and antiviral function. Autophagy, a process of bulk protein degradation through an autophagosomic lysosomal pathway, is important for differentiation, survival during nutrient deprivation, and normal growth control, and is often defective in tumor cells. Beclin 1 was originally isolated in a yeast two hybrid screen to identify Bcl 2 binding partners and maps to a tumor susceptibility locus on human chromosome 17q21 that is frequently monoallelically deleted in human breast, ovarian and prostate cancer. Beclin 1 encodes an evolutionarily conserved 52kDa coiled coil protein that is expressed in human muscle, epithelial cells and neurons.
.pecificity :
- Anti- Cav-1 is a rabbit polyclonal antibody unconjugated
specific for Cav-1 of hu, rat, mo
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– Protein G affinity chromatography purification, purity :>95%
– Isotype: IgG
Application : Rabbit Anti- Cav-1抗体说明书，新学期*
– WB=1:100-500
– ELISA=1:500-1000
– IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 ，not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user..
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rabbit Anti- Cav-1抗体说明书，新学期*
